Research Paper Volume 12, Issue 17 pp 17305—17327
Chloride intracellular channel protein 2: prognostic marker and correlation with PD-1/PD-L1 in breast cancer
Figure 6. TIMER found CLIC2 highly expressed cancer was accompanied by increased TILs. (A) TIMER was performed to assess the correlation between CLIC2 expression and six types of TILs enrichment cross all subtypes of BC. Other than B cells and macrophages, CLIC2 expression has a strong positive correlation with CD8+ T cells, and moderate correlation with CD4+ T cells, neutrophils, and dendritic cells in BC. TIMER database analysis in (B) basal, (C) HER-2 and (D) luminal subtypes. TIMER, Tumor Immune Estimation Resource; TILs, tumor infiltration lymphocytes.