Research Paper Volume 12, Issue 20 pp 20152—20162
Polymerase I and transcript release factor transgenic mice show impaired function of hematopoietic stem cells
PTRF altered the expression pattern of senescence-associated genes in LSKs. (A–C) RT-PCR analysis of the indicated genes in sorted LSK cells from PTRF and WT mice. Data represent the mean ± SD of three independent experiments. *, P < 0.05; **, P < 0.01. Data were normalized against GAPDH expression.