Research Paper Volume 12, Issue 20 pp 20163—20183

Down-regulated ciRS-7/up-regulated miR-7 axis aggravated cartilage degradation and autophagy defection by PI3K/AKT/mTOR activation mediated by IL-17A in osteoarthritis

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Representative images of safranin O-stained rat knee joint sections with different treatments and the related Mankin’s scores of each group. Data represent the mean ± SD (n = 10), * p < 0.05, ** p < 0.01 and *** p < 0.001 vs. IL-1β group.