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Research Paper Volume 12, Issue 17 pp 17380—17392

Identification of a cullin5-RING E3 ligase transcriptome signature in glioblastoma multiforme

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Figure 3. Expression of CRL5 components in GBM. (A) Boxplot data analysis of genes encoding CRL5 components in GBM and normal brain tissues. GEPIA (http://gepia.cancer-pku.cn/) was used to analyze RNA-seq data from malignant and normal tissues (TCGA and GTEx datasets). (B) In situ hybridization of SOCS3 and CUL5 in GBM patients based on the Ivy GAP dataset. * P < 0.01.