Research Paper Volume 12, Issue 17 pp 17541—17567

Figure 8. Functional protein interaction network of BRD-containing protein genes (STRING and DAVID). (A) Protein interaction network of 50 functional partners with confidence score > 0.9 based on STRING database. BRD 1/2/3/4/7/8/9 are the seed genes. Ten interacting partners with the highest confident scores were colored and placed in the outer shell. The other forty interacting partners were grey and placed in the inner shell. The blue lines represent the correlation between proteins and the thickness of the lines indicates the strength of data support. (B–C) The bubble diagram displayed the GO functional enrichment results of the 50 functional interactors, including biological process and cellular components.