Figure 4. Amyloid peptides load in the brain of 3xTg-AD mice. Levels of Aβ(1-42) (panel A) and Aβ(1-40) (panel B) peptides measured by ELISA on brain homogenates of 3xTg-AD mice, T0, C, LAB and p62-LAB groups. Concentrations are expressed as pg/mL (**p<0.01 and ***p<0.001 vs T0, #p<0.05 and ##p<0.01 vs C, §p<0.05 vs LAB).