Research Paper Volume 12, Issue 20 pp 20523—20539

Effect of exosomal UCA1 on esophageal cancer cells. (A) Expression of UCA1 in EC18 and Kyse140 cells treated with exosomes derived from NEEC cells transfected with UCA1-expressing plasmids (UCA1-Exo) or negative control plasmids (Control- Exo). (B, C) Cell viability of EC18 and Kyse140 cells treated with exosomes derived from NEEC cells transfected with UCA1-expressing plasmids (UCA1-Exo) or negative control plasmids (Control- Exo). (D) Invasive ability of EC18 and Kyse140 cells treated with exosomes derived from NEEC cells transfected with UCA1-expressing plasmids (UCA1-Exo) or negative control plasmids (Control- Exo). Scale bar = 50 nm. (E) Migratory ability of EC18 and Kyse140 cells treated with exosomes derived from NEEC cells transfected with UCA1-expressing plasmids (UCA1-Exo) or negative control plasmids (Control- Exo). Scale bar = 50 nm. (F) Colony formation ability of EC18 and Kyse140 cells treated with exosomes derived from NEEC cells transfected with UCA1-expressing plasmids (UCA1-Exo) or negative control plasmids (Control- Exo). (*) denotes the difference between groups (P<0.05). Each experiment had a minimum of three replicates per treatment group.