Research Paper Volume 12, Issue 20 pp 20587—20610

Multiomics integrative analysis for gene signatures and prognostic values of m6A regulators in pancreatic adenocarcinoma: a retrospective study in The Cancer Genome Atlas project

class="figure-viewer-img"

Landscape of somatic mutation status of m6A regulators in PAAD. (A) The mutation frequency of 24 m6A regulators in 177 patients from TCGA_PAAD cohort. Each column represented individual patients. The upper barplot showed tumor mutation burden (TMB). (B) The mutation frequency of 24 m6A regulators in 616 patients from ICGC_AU_PAAD and ICGC_CA_PAAD cohort. The upper barplot showed mutation events happeded in per 1 million bases. Due to the difference in the definition and naming of somatic mutations, it is unable to integrate (A) and (B) into the same waterfall chart.