Construction of a nomogram for overall survival prediction in HNSCC. (A) Univariate and multivariate Cox regression analyses of clinical factors associated with overall survival. (B) The nomogram consists of M stage, new event, stage and the signature score based on the eight-lncRNA signature. (C) ROC curves according to the nomogram and lncRNA signature score. (D) Calibration curves of the nomogram for the estimation of survival rates at 3 and 5 years. (E) Kaplan-Meier curves of OS according to the total risk score.