Figure 4. HIPK3 correlated with various clinicopathological parameters in ccRCC tissues. The mRNA levels of HIPK3 were compared in different clinicopathological parameters: (A) overall survival status, (B) disease free status cancer versus paired para-cancer, (C) M stage, (D) and (E) T stage, (F) and (G) grade, (H) and (I) TNM stage. S: TNM stage; HIPK, Homeodomain interacting protein kinases. *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001.