Research Paper Volume 13, Issue 3 pp 3588—3604

Downregulation of circFASTKD1 ameliorates myocardial infarction by promoting angiogenesis

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Figure 6. The downregulation of circFASTKD1 benefits vascular endothelial cells under hypoxic conditions. (A, B) qRT-PCR was used to determine circFASTKD1 levels in HUVECs (A) and HCMECs (B) under hypoxic conditions. (C, D) CCK-8 assays were used to determine the growth curves of HUVECs (C) and HCMECs (D) with up/downregulated circFASTKD1 under hypoxic conditions. (E) Photographs from the tube formation, cell migration and wound healing assays in HUVECs with different treatments under hypoxic conditions. (FH) Quantitative analyses of the tube formation (F), cell migration (G) and wound healing (H) assays in HUVECs under hypoxic conditions.