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Research Paper Volume 13, Issue 3 pp 4482—4502

Identification of downstream signaling cascades of ACK1 and prognostic classifiers in non-small cell lung cancer

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Figure 1. The implication of ACK1 in NSCLC. Genetic alterations of the ACK1 gene in the TCGA-LUAD and TCGA-LUSC cohorts (A) (https://www.cbioportal.org). The association between ACK1 gene copy number and mRNA expression levels (B). Significantly elevated mRNA expression levels of the ACK1 gene in lung cancer in comparison with normal tissues in the independent cohorts from the Oncomine database (C). Immunohistochemistry of ACK1 in lung cancer (D, Human Protein Atlas). Abbreviation: FC, fold change.