Integrated analysis of microRNA and mRNA expression profiling identifies <i>BAIAP3</i> as a novel target of dysregulated hsa-miR-1972 in age-related white matter lesions

Wen-Qing Huang; Qing Lin; Shuai Chen; Lixiang Sun; Qingjie Chen; Kehui Yi; Zhi Li; Qilin Ma; Chi-Meng Tzeng

doi:doi:10.18632/aging.202562

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Research Paper Volume 13, Issue 3 pp 4674—4695

Integrated analysis of microRNA and mRNA expression profiling identifies BAIAP3 as a novel target of dysregulated hsa-miR-1972 in age-related white matter lesions

Figure 4. Functional enrichment analysis of miRNA targets using Cytoscape. (A–C) Cellular component enrichment analysis of the predictive targets of miR-1972(A), miR-3141(B) and miR-26b-5p (C). The putative targets of miRNA were predicted by TargetScan 7.1 software. The functional enrichment analysis was performed by the ClueGO tool in Cytoscape software. (D). The functional enrichment of the 98 shared genes, shown in Figure 3A. *P < 0.05, **P <0.01.