Single-cell RNA sequencing of human femoral head <i><i>in vivo</i></i>

Xiang Qiu; Ying Liu; Hui Shen; Zun Wang; Yun Gong; Junxiao Yang; Xiaohua Li; Huixi Zhang; Yu Chen; Cui Zhou; Wanqiang Lv; Liang Cheng; Yihe Hu; Boyang Li; Wendi Shen; Xuezhen Zhu; Li-Jun Tan; Hong-Mei Xiao; Hong-Wen Deng

doi:doi:10.18632/aging.203124

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Research Paper Volume 13, Issue 11 pp 15595—15619

Single-cell RNA sequencing of human femoral head in vivo

Figure 1. scRNA-seq reveals the cell populations of the human femoral head. (A) Study overview. (B) After QC, the number of genes (left) and RNA molecules (right). (C) t-SNE plot shows the color-coded clustering of human femoral head tissue cells. (D) Heat map shows the top 10 genes with the highest avg_logFC of each cluster. (E) The proportion of each cluster (left) and each cell type (right). scRNA-seq: single-cell RNA sequencing: Gran: granulocyte; Mono: monocyte; RBC: red blood cell; OBC: osteoblastic lineage cell; EC: endothelial cell; EPC: endothelial progenitor cell; PDC: plasmacytoid dendritic cell.