Research Paper Volume 13, Issue 13 pp 17830—17846
Linc00941 regulates esophageal squamous cell carcinoma via functioning as a competing endogenous RNA for miR-877-3p to modulate PMEPA1 expression
Figure 7. Knockdown of linc00941 suppressed EMT via miR-877-3p/PMEPA1 axis in KYSE-510 cells. (A–D) qRT-PCR determined the mRNA expression of vimentin, N-cadherin, Snail and E-cadherin in KYSE-510 cells transfected with linc00941 siRNA, miR-877-3p inhibitors, pcDNA-PMEPA1 or the respective controls. (E) Western blot assay determined the protein expression of vimentin, N-cadherin, Snail and E-cadherin in KYSE-510 cells transfected with linc00941 siRNA, miR-877-3p inhibitors, pcDNA-PMEPA1 or the respective controls. N = 3. *P<0.05, **P<0.01 and ***P<0.001 compared between different treatment groups.