Research Paper Volume 14, Issue 4 pp 2004—2013
MKRN2 inhibits the proliferation of gastric cancer by downregulating PKM2
Figure 2. Effect of MKRN2 modulation on gastric cancer cells in vitro. SGC-7901 and MGC-803 cells were transfected with lentiviral vector containing MKRN2 (pLV-MKRN2) or negative control vector (pLV-NC). Cell proliferation was determined by CCK8 assay and colony formation assay in the SGC-7901 and MGC-803 cells transfected with MKRN2 mimics. Representative photos from the colony formation assay in the SGC-7901 and MGC-803 cells transfected with pLV-MKRN2, pLV-NC. (A, C, E, *: P<0.05). An opposite outcome was found when SGC-7901 and MGC-803 cells were transfected with si-MKRN2 or si-NC (B, D, F,*: P<0.05).