Research Paper Volume 14, Issue 4 pp 2004—2013

Figure 3. Overexpression of MKRN2 inhibits xenograft tumor growth in vivo. Xenograft tumors from GC cells with MKRN2 overexpression (MGC-803 and SGC-7901) grew much slower than the tumors from the control cells (transfected with pLV-NC). (A) Upon harvest, the xenograft tumors from the MKRN2-overexpressing cells were much smaller in size and weight than the tumors from the control cells (transfected with pLV-NC). (B, C) Western blot assay showed that the MKRN2 expression of xenograft tumor in experimental group was higher than control group in mice. (D–F) *: P<0.05, **: P<0.01.