Matairesinol exerts anti-inflammatory and antioxidant effects in sepsis-mediated brain injury by repressing the MAPK and NF-κB pathways through up-regulating AMPK

Qin Wu; Yuhua Wang; Qingfang Li

doi:doi:10.18632/aging.203649

← Back

Research Paper Volume 13, Issue 20 pp 23780—23795

Matairesinol exerts anti-inflammatory and antioxidant effects in sepsis-mediated brain injury by repressing the MAPK and NF-κB pathways through up-regulating AMPK

Figure 5. Mat choked the CLP-activated MAPK and NF-κB pathways. Experimental animals were treated like that in Figure 3. (A–B) The profiles of Nrf2, HO-1, MAPK P38, JNK and NF-κB were tested by WB. ^***P < 0.001 (vs. sham group). ns P > 0.05, ⁺P < 0.05, ⁺⁺P < 0.01, ⁺⁺P < 0.001 (vs. CLP group).