Volume 13, Issue 20

31 October, 2021
pp 23435—23871

About the Cover

The cover features Figure 5 " Top traits determined by three independent methods“ from Sun et al.

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Table of Contents

Editorials

DNA repair in cancer development and aging

Hua Zhao, Bernard F. Fuemmeler, Jie Shen,

https://doi.org/10.18632/aging.203656 pp 23435—23436

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MCPH1, beyond its role deciding the brain size

Martina Kristofova, Zhao-Qi Wang,

https://doi.org/10.18632/aging.203658 pp 23437—23439

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Scaffolding proteins in pediatric glioma

Caroline Capdevielle, Martin Hagedorn,

https://doi.org/10.18632/aging.203659 pp 23440—23441

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Research Papers

COVID-19
Serum amylase elevation is associated with adverse clinical outcomes in patients with coronavirus disease 2019

Ganxun Li, Tongtong Liu, Guannan Jin, Tianhong Li, Junnan Liang, Qian Chen, Lin Chen, Wei Wang, Yuwei Wang, Jia Song, Huifang Liang, Chuanhan Zhang, Peng Zhu, Wanguang Zhang, Zeyang Ding, Xiaoping Chen, Bixiang Zhang, Tongji Multidisciplinary Team for Treating COVID-19 (TTTC),

https://doi.org/10.18632/aging.203653 pp 23442—23458

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COVID-19
COVID-19: risk factors for severe cases of the Delta variant

Kaiyuan Hu, Liu Lin, Ying Liang, Xinning Shao, Zhongwei Hu, Hongbin Luo, Ming Lei,

https://doi.org/10.18632/aging.203655 pp 23459—23470

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Predicting physiological aging rates from a range of quantitative traits using machine learning

Eric D. Sun, Yong Qian, Richard Oppong, Thomas J. Butler, Jesse Zhao, Brian H. Chen, Toshiko Tanaka, Jian Kang, Carlo Sidore, Francesco Cucca, Stefania Bandinelli, Gonçalo R. Abecasis, Myriam Gorospe, Luigi Ferrucci, David Schlessinger, Ilya Goldberg, Jun Ding,

https://doi.org/10.18632/aging.203660 pp 23471—23516

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A genetic determinant of VEGF-A levels is associated with telomere attrition

Vesna Gorenjak, Alexandros M. Petrelis, Maria G. Stathopoulou, Simon Toupance, Satish Kumar, Carlos Labat, Christine Masson, Helena Murray, John Lamont, Peter Fitzgerald, Athanase Benetos, Sophie Visvikis-Siest, TELARTA Consortium,

https://doi.org/10.18632/aging.203636 pp 23517—23526

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NEOage clocks - epigenetic clocks to estimate post-menstrual and postnatal age in preterm infants

Stefan Graw, Marie Camerota, Brian S. Carter, Jennifer Helderman, Julie A. Hofheimer, Elisabeth C. McGowan, Charles R. Neal, Steven L. Pastyrnak, Lynne M. Smith, Sheri A. DellaGrotta, Lynne M. Dansereau, James F. Padbury, Michael O’Shea, Barry M. Lester, Carmen J. Marsit, Todd M. Everson,

https://doi.org/10.18632/aging.203637 pp 23527—23544

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Profound synchrony of age-specific incidence rates and tumor suppression for different cancer types as revealed by the multistage-senescence model of carcinogenesis

Richard B. Richardson, Catalina V. Anghel, Dennis S. Deng,

https://doi.org/10.18632/aging.203651 pp 23545—23578

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AHNAK suppresses ovarian cancer progression through the Wnt/β-catenin signaling pathway

Yanlin Cai, Yi Hu, Furong Yu, Wenjuan Tong, Shufen Wang, Shunliang Sheng, Jiayu Zhu,

https://doi.org/10.18632/aging.203473 pp 23579—23587

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ALDH2 promotes uterine corpus endometrial carcinoma proliferation and construction of clinical survival prognostic model

Yun-Qian Cui, Yuan Xiang, Fei Meng, Chun-Hui Ji, Rui Xiao, Jia-Peng Li, Zhou-Tong Dai, Xing-Hua Liao,

https://doi.org/10.18632/aging.203605 pp 23588—23602

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Resveratrol promotes axonal regeneration after spinal cord injury through activating Wnt/β-catenin signaling pathway

Zimin Xiang, Shuai Zhang, Xiaodong Yao, Libin Xu, Jianwei Hu, Chenghui Yin, Jianmei Chen, Hao Xu,

https://doi.org/10.18632/aging.203628 pp 23603—23619

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Nmnat2 attenuates amyloidogenesis and up-regulates ADAM10 in AMPK activity-dependent manner

Xiang-Shu Cheng, Fang-Xiao Shi, Kun-Peng Zhao, Wang Lin, Xiao-Ying Li, Jun Zhang, Yao-Yao Bu, Rui Zhu, Xiao-Hong Li, Dong-Xiao Duan, Xin-Ying Ji, Jian-She Wei, Jian-Zhi Wang, Jin Du, Xin-Wen Zhou,

https://doi.org/10.18632/aging.203634 pp 23620—23636

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Comprehensive analysis of prognostic genes in gastric cancer

Shaohua Huang, Liping Ma, Biyang Lan, Ning Liu, Wenwei Nong, Zhihu Huang,

https://doi.org/10.18632/aging.203638 pp 23637—23651

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Up-regulation of SIRT1 induced by 17beta-estradiol promotes autophagy and inhibits apoptosis in osteoblasts

Yu Wang, Runhong Mei, Shimin Hao, Peng Luo, Penghao Wang, Yaser Almatari, Lei Guo, Lan Guo,

https://doi.org/10.18632/aging.203639 pp 23652—23671

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Differences in and verification of genetic alterations in chemotherapy and immunotherapy for metastatic melanoma

Yang Li, Yuling Gao, Weiling Chu, Jianjian Lv, Zhi Li, Tongxin Shi,

https://doi.org/10.18632/aging.203640 pp 23672—23688

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Analysis of gut microbiota and metabolites in patients with rheumatoid arthritis and identification of potential biomarkers

Yumei Chen, Chiyu Ma, Lixiong Liu, Jingquan He, Chengxin Zhu, Fengping Zheng, Weier Dai, Xiaoping Hong, Dongzhou Liu, Donge Tang, Yong Dai,

https://doi.org/10.18632/aging.203641 pp 23689—23701

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Selected ideal natural ligand against TNBC by inhibiting CDC20, using bioinformatics and molecular biology

Naimeng Liu, Xinhui Wang, Zhu Zhu, Duo Li, Xiaye Lv, Yichang Chen, Haoqun Xie, Zhen Guo, Dong Song,

https://doi.org/10.18632/aging.203642 pp 23702—23725

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Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling

Yongjing Lai, Lihua Dong, Huifang Jin, Hongju Li, Meiling Sun, Jianlan Li,

https://doi.org/10.18632/aging.203645 pp 23726—23738

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Loganin substantially ameliorates molecular deficits, pathologies and cognitive impairment in a mouse model of Alzheimer’s disease

Lulin Nie, Kaiwu He, Fengzhu Xie, Shifeng Xiao, Shupeng Li, Jia Xu, Kaiqin Zhang, Chen Yang, Li Zhou, Jianjun Liu, Liangyu Zou, Xifei Yang,

https://doi.org/10.18632/aging.203646 pp 23739—23756

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Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis

Yan Zheng, Ben Niu, Weihua Zhang, Xingli Ru, Ying Gao, Chuancui Li, Xifeng Wu,

https://doi.org/10.18632/aging.203647 pp 23757—23768

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Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis

Yiqiong Yang, Jing Wang, Yu Zhang, Xiuxiu Hu, Li Li, Pingsheng Chen,

https://doi.org/10.18632/aging.203648 pp 23769—23779

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Matairesinol exerts anti-inflammatory and antioxidant effects in sepsis-mediated brain injury by repressing the MAPK and NF-κB pathways through up-regulating AMPK

Qin Wu, Yuhua Wang, Qingfang Li,

https://doi.org/10.18632/aging.203649 pp 23780—23795

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Clinicopathological and prognostic value of long noncoding RNA SNHG7 in cancers: a meta-analysis and bioinformatics

June Wang, Shenlin Du, Chen Wang, Zinian Zhu, Baocheng Xie, Bashan Zhang,

https://doi.org/10.18632/aging.203650 pp 23796—23809

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CCR5 is a prognostic biomarker and an immune regulator for triple negative breast cancer

Xin Wang, Yong Han, Jiamin Peng, Jie He,

https://doi.org/10.18632/aging.203654 pp 23810—23830

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CircFAM120B knockdown inhibits osteosarcoma tumorigenesis via the miR-1205/PTBP1 axis

Jia-Ju Li, Ming-Yue Xiong, Tian-Yu Sun, Chang-Bin Ji, Run-Tao Guo, Ya-Wei Li, Hong-Yu Guo,

https://doi.org/10.18632/aging.203657 pp 23831—23841

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Review

Differential expression of long non-coding RNAs as diagnostic markers for lung cancer and other malignant tumors

Li Li, Haitao Wei, Yi Wei Zhang, Shizhe Zhao, Guowei Che, Yun Wang, Longqi Chen,

https://doi.org/10.18632/aging.203523 pp 23842—23867

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Corrections

Correction for: CircRNA_100367 regulated the radiation sensitivity of esophageal squamous cell carcinomas through miR-217/Wnt3 pathway

Junqi Liu, Nannan Xue, Yuexin Guo, Kerun Niu, Liang Gao, Song Zhang, Hao Gu, Xin Wang, Di Zhao, Ruitai Fan,

https://doi.org/10.18632/aging.203664 pp 23868—23870

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Correction for: YKL40 in sporadic amyotrophic lateral sclerosis: cerebrospinal fluid levels as a prognosis marker of disease progression

Pol Andrés‐Benito, Raúl Domínguez, Maria J. Colomina, Franc Llorens, Mònica Povedano, Isidre Ferrer,

https://doi.org/10.18632/aging.203667 pp 23871

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