Research Paper Volume 14, Issue 2 pp 747—769
Overexpression of chaperonin containing TCP1 subunit 7 has diagnostic and prognostic value for hepatocellular carcinoma
Figure 4. CCT7 has a higher PPV than AFP for HCC diagnosis. CCT7 mRNA levels were significantly greater in HCC than in non-HCC tissues in GSE25097 (A), GSE63898 (B) and TCGA LIHC datasets (C). In ROC curve analyses, CCT7 had a significantly higher AUC than AFP in the GSE25097 (0.719 vs. 0.677, D), GSE63898 (0.803 vs. 0.567, E) and TCGA LIHC datasets (0.743 vs. 0.616, F). CCT7 had a higher PPV than AFP in the GSE25097 (54.9% vs. 44.1%, G), GSE63898 (64.5% vs. 28.1%, H) and TCGA LIHC datasets (55.8% vs. 41.3%, I).