Research Paper Volume 14, Issue 2 pp 747—769

Overexpression of chaperonin containing TCP1 subunit 7 has diagnostic and prognostic value for hepatocellular carcinoma


Figure 6. Dysregulated CCT7 expression is associated with DNA methylation status in HCC patients. (A) CCT7 mRNA expression in different copy number groups. (B) The correlation between CCT7 mRNA expression and DNA methylation status. (C) The heat map shows CCT7-related methylated CpG sites in HCC. (D) The forest map shows the correlation between CpG site methylation and survival times in HCC patients. (E) The correlation between CCT7 mRNA expression and cg19515186 methylation status. (F) ROC curve analysis showing the significant diagnostic value of cg19515186 methylation status for HCC in TCGA. (G) Survival analysis showing that higher methylation of cg19515186 was associated with better OS in HCC patients.