Research Paper Volume 14, Issue 2 pp 747—769

Overexpression of chaperonin containing TCP1 subunit 7 has diagnostic and prognostic value for hepatocellular carcinoma


Figure 9. High CCT7 expression is associated with spliceosome gene expression in HCC patients. (A, B) The 45 genes co-expressed with CCT7 in HCC tissues, based on the GO Biological Process analysis (A) and KEGG pathway analysis (B). (C) The most significant survival-associated genes in HCC tissues, based on KEGG pathway analysis of data from the GEPIA database. (D) Heat map showing the median mRNA levels of genes co-expressed with CCT7 in HCC tissues in the GSEA. (E) The main enriched KEGG pathways of CCT7 based on GSEA. SPLICEOSOME (a), RIBOSOME (b), OXIDATIVE PHOSPHORYLATION (c), PROTEIN EXPORT (d), DNA REPLICATION (e), NUCLEOTIDE EXCISION PEPAIR (f), MISMATCH REPAIR (g), PENTOSE PHOSPHATE PATHWAY (h).