COVID-19 Research Paper Volume 14, Issue 1 pp 73—108
Decreased TMPRSS2 expression by SARS-CoV-2 predicts the poor prognosis of lung cancer patients through metabolic pathways and immune infiltration
Figure 8. Association between TMPRSS2 expression and infiltration levels of immune cells in lung cancer. (A) TMPRSS2 expression was significantly correlated with the infiltration levels of various immune cells in LUAD and LUSC in the TIMER database. (B, C) TMPRSS2 expression was significantly associated with the infiltration of immune cells in LUAD and LUSC according to the CIBERSORT algorithm. (D) Heatmap of the correlation of TMPRSS2 and immune checkpoints in LUAD. (E) Heatmap of the correlation of TMPRSS2 and immune checkpoints in LUSC. *p < 0.05, **p < 0.01, ***p < 0.001.