Figure 1. Schematic diagram of the study design. (A) A new prognostic model related to pyroptosis has been established from the literature and databases. (B) The stability and generalisability of the model was verified in an external independent database. (C) Prediction and application of PRS for clinical response to treatment. LASSO, least absolute shrinkage and selection operator; PRS, Pyroptosis-related Risk Scores; AUC, area under the curve.