Research Paper Volume 14, Issue 2 pp 989—1013
A novel pyroptosis-related signature predicts prognosis and response to treatment in breast carcinoma
Figure 4. Validation of the gene signature in the external validation sets. The distribution and cutoff value of the risk score in the groups in the GSE20685 (A) and GSE21653 (B). The distributions of OS status, OS and the risk score in the GSE20685 (C) and GSE21653 (D). The expression heatmap of the 15 pyroptosis-related prognostic genes between the high and low-PRS groups in the GSE20685 (E) and GSE21653 (F). Kaplan-Meier curves for the OS of patients in the high-risk group and low-risk group in the GSE20685 (G) and GSE21653 (H) cohorts. TCGA, The Cancer Genome Atlas; GSE, gene expression omnibus series; OS, overall survival; PRS, pyroptosis-related risk score; High-PRS, high pyroptosis-related risk score; Low-PRS, low pyroptosis-related risk score.