Research Paper Volume 14, Issue 2 pp 728—746

Figure 4. Increasing the number of miRs associated with an individual gene promotes mRNA downregulation. (A) Each bar represents the proportion of mRNAs (y-axis) that were upregulated on day 1 (blue bar) and day 4 (orange bar) or downregulated on day 1 (black bar) and day 4 (white bar) and were associated with 1 to ≥10 of the 22 miRs (x-axis) that increase in older males. (B) Collapsing the data to show that the percent of gene expression associated with 1–2 or ≥3 miRs. Note that on day 4, mRNA associated with ≥3 miRs are more likely to be downregulated.