Research Paper Volume 14, Issue 4 pp 1651—1664
Mitochondrial dysfunction in mandibular hypoplasia, deafness and progeroid features with concomitant lipodystrophy (MDPL) patients
Figure 1. mtDNA copy number and quantification of mitochondrial markers in HDFs WT and MDPL. (A) Comparison of mtDNA copy number between WT and MDPL. mtDNA copy number are reported as mean ± standard deviation. *p < 0.05. (B) Quantification of mRNA levels of MFN1, MFN2, MFF, PARKIN, SIRT1, TFAM transcription factors, GPX1 in MDPL and control fibroblasts (WT). Data are from three independent experiments and represented as mean ± SD; (*p < 0.05 **p < 0.01).