Research Paper Volume 15, Issue 6 pp 1859—1877
P53/miR-34a/SIRT1 positive feedback loop regulates the termination of liver regeneration
Figure 1. P53/miR-34a/SIRT1 positive feedback loop expression during LR. (A) Protein expression of the P53/miR-34a/SIRT1 positive feedback loop during LR progression was analyzed via western blot. (B) Quantification of hepatic P53, Ace-P53, and SIRT1 expression at the indicated time points after PH by WB. (C) Quantification of hepatic miR-34a expression at the indicated time points after PH by qPCR. (ns: not significant, p>0.05; *, p<0.05; **, p<0.01; ***, p<0.001).