Research Paper Volume 14, Issue 4 pp 1983—2003
Pseudogene AK4P1 promotes pancreatic ductal adenocarcinoma progression through relieving miR-375-mediated YAP1 degradation
Figure 5. Four hub genes are identified as functional target genes of AK4P1. (A) The expression correlation between AK4P1 and four hub genes (CTNNB1, YAP1, PSEN1, and SP1) in PDAC was assessed using GEPIA. (B) Box-whisker plot represented expression of four hub genes (CTNNB1, YAP1, PSEN1, and SP1) in PDAC and normal pancreas tissues were determined by GEPIA. (C) Expression of four hub genes (CTNNB1, YAP1, PSEN1, and SP1) among major stages in PDAC were determined by GEPIA. (D) Prognostic role (OS) of four hub genes (CTNNB1, YAP1, PSEN1, and SP1) expression in PDAC. (E) Prognostic role (DFS) of four hub genes (CTNNB1, YAP1, PSEN1, and SP1) expression in PDAC. Three horizontal lines in the box plot represent minimum, median and maximum, respectively. *P < 0.05.