Research Paper Volume 14, Issue 8 pp 3446—3463

Figure 5. Effect of CXCL14 on cell proliferation and migration. (A) Western blot of CXCL14 in three treatment groups. Z138 and G519 cells were grown and transiently transfected with CXCL14 or negative control for 48 h and then subjected to western blotting. (B) Quantified band intensities in Z138 cell lines. (C) Quantified band intensities in G519 cell lines. The dotted line indicates the reference integrated density (control group). (D) Knockdown of CXCL14 on cell proliferation in Z138 cells. (E) Knockdown of CXCL14 on cell proliferation in G519 cells. The reference proliferation rate was defined as in the control group in each day. (F) Knockdown of CXCL14 on cell migration in Z138 cells. (G) Knockdown of CXCL14 on cell migration in G519 cells. The reference migration rate was defined as in the control group. Significance: ^***P < 0.001, ^**P < 0.01, ^*P < 0.05. (H) High expressed CXCL14 promotes cell migration and aggravates mantle cell lymphoma.