Research Paper Volume 14, Issue 12 pp 5059—5074
The circular RNA hsa_circ_0003091 regulates sepsis-induced lung injury by sponging the miR-149/Smad2 axis
Figure 7. mmu_circ_0015268 inhibited LPS-induced lung injury via the miR-149/Smad2 axis. The PMLECs were transfected with mmu_circ_0015268-expressing vector and miR-149 mimics alone or combined, followed by LPS stimulation. (A) Expression of Smad2 in different groups. (B) Western blot of BAX, BCL2, Caspase3, cleaved PARP1, E-selectin, intercellular cell adhesion molecule-1 (ICAM1), vascular cell adhesion protein 1 (VCAM1), P120-catenin, β-catenin, and E-cadherin in different groups. **p < 0.01; ***p < 0.001.