Research Paper Volume 14, Issue 12 pp 5075—5085
The minor allele of rs17427875 in long non-coding RNA-HOXA11-AS influences the prognosis of subarachnoid hemorrhage (SAH) via modulating miR-15a and STAT3 expression
Figure 2. Compared with SAH patients carrying the AT genotype of rs17427875, in the peripheral blood samples, the relative expressions of lncRNA-HOXA11-AS (A) was significantly increased while the relative expression level of miR-15a (B) was notably repressed, and both the TNF-α (C) and NF-κB (D) level were significantly increased in SAH patients carrying the AT genotype of rs17427875. Moreover, similar results were observed of lncRNA-HOXA11-AS (E), miR-15a (F), TNF-α (G) and NF-κB (H) in the CSF samples collected from SAH patients carrying the AT genotype of rs17427875 (*P value < 0.05 vs. AA group).