Research Paper Volume 14, Issue 12 pp 5116—5130

Figure 1. Flow diagram showing study participant selection. For patients who received intravitreal anti-vascular endothelial growth factor (VEGF) treatment, the index date was the day of the first intravitreal anti-vascular endothelial growth factor injection. For patients who did not receive intravitreal anti-vascular endothelial growth factor treatment, the index date was nested with the paired anti-VEGF patients. All study participants were at risk on the index date. Abbreviations: AMD: age-related macular degeneration; B group: 2005 Longitudinal Health Insurance Databases; CNV: choroidal neovascularization; DME: diabetic macular edema; PCV: polypoidal choroidal vasculopathy; PSM: propensity Score Matching; VEGF: vascular endothelial growth factor.