Research Paper Volume 14, Issue 12 pp 4990—5012

Sus1 maintains a normal lifespan through regulation of TREX-2 complex-mediated mRNA export

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Figure 3. TREX-2 affects RLS in a Sir2-independent manner. (AC) RLS analysis of double deletion strains of SAGA DUB mutants (A), sus1Δ mutants (B) and TREX-2 mutants (C) in combination with sir2Δ. The mean lifespans are shown in parentheses. (D and E) Growth analysis of the strains used in (AC), as described in Figure 1E.