Figure 3. TREX-2 affects RLS in a Sir2-independent manner. (A–C) RLS analysis of double deletion strains of SAGA DUB mutants (A), sus1Δ mutants (B) and TREX-2 mutants (C) in combination with sir2Δ. The mean lifespans are shown in parentheses. (D and E) Growth analysis of the strains used in (A–C), as described in