Research Paper Volume 14, Issue 16 pp 6689—6715
Prognostic alternative splicing events related splicing factors define the tumor microenvironment and pharmacogenomic landscape in lung adenocarcinoma
Figure 7. Characteristics of SFscore in prognosis and TME landscapes. (A) Differences in the SFscore between three SF clusters in LUAD (P < 2.22e-16). (B) Differences in the SFscore between two gene clusters in LUAD (P < 2.22e-16). (C) Kaplan-Meier curves for low and high SFscore patient groups in GEO cohorts (P < 0.001, Log-rank test). (D) Kaplan-Meier curves for low and high SFscore patient groups were validated in TCGA cohorts (P < 0.001, Log-rank test). (E) Alluvial diagram showing the changes of survival status, SFs clusters, gene clusters and SFscore. (F) GSVA enrichment analyses between groups with low/high SFscore. (G) TME cell infiltrating abundances in low/high SFscore groups. (H) Difference of immune functions in low/high SFscore groups. (I) Difference of other tumor-related biological processes in low/high SFscore groups.