Research Paper Volume 14, Issue 17 pp 6917—6935
Identification of immune subtypes to guide immunotherapy and targeted therapy in clear cell renal cell carcinoma
Figure 7. Identification of potential tumor antigens in ccRCC. (A) Identification of potential tumor-associated antigens in ccRCC through differential expression analysis. Chromosomal distribution of up- and down-regulated genes in ccRCC, as indicated. (B, C) Identification of potential tumor-associated antigens in ccRCC through fraction of the genome altered and mutation analysis. (D) Combined analysis of multiple spectra to identify specific antigens. (E, F) The association of SCG2 with OS and PFS. (G) The correlation between SCG2 and immune cells (Tregs and CAFs) in pan-cancer. (H) Differential expression of SCG2 among the ccRCC immune subtypes in TCGA cohorts. Tregs: regulatory T cell; CAFs: cancer associated fibroblast.