Research Paper Volume 14, Issue 19 pp 7650—7661
Senolytic elimination of senescent macrophages restores muscle stem cell function in severely dystrophic muscle
Figure 1. mdx/utro(−/−) muscle exhibits obvious stem cell exhaustion, immune cell infiltration and cellular senescence. (A) Immunofluorescent staining of Pax7 and Collagen type IV in muscle tissues of WT and mdx/utro(−/−) mice. (B) Immunofluorescent staining of CD68 in muscle tissues of WT and mdx/utro(−/−) mice. (C) Staining of SA-β-Gal in muscle tissues of WT and mdx/utro(−/−) mice. n = 8 mice/group for statistics, and data are presented as mean +/− SD.