Research Paper Volume 14, Issue 19 pp 7824—7850

Figure 3. Different clinical and transcriptome characteristics of the three DNA methylation regulator patterns in the gather glioma cohort. (A) Heatmap of several immune signatures for the three DNA methylation regulator patterns in the gather glioma cohort. (B) Box-plots show the expression levels of few stroma-activated related genes in the three DNA methylation regulator patterns based on the gather glioma cohort. (C) Box-plots show the proportions of several immune cells types in the three patterns based on the gather glioma cohort. (D) Box-plots show the TMB for the three patterns in the TCGA dataset. (E) Functional annotation of the DNA methylation related genes between three patterns in the gather glioma cohort. Note: ns P > 0.05; ^*P < 0.05; ^**P < 0.01; ^***P < 0.001.