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Research Paper Volume 14, Issue 20 pp 8302—8320

Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats

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Figure 5. Tanshinone IIA (TIIA) preserved mitochondrial biogenesis and dynamics in renal ischemia-reperfusion (IR)-induced renal injury. The expression of PGC-1α, Nrf1, and Tfam in mRNA and protein level. The expression of Mfn1, Mfn2, and Drp1 in mRNA (A) and protein (B) levels. *p < 0.05 versus sham group, #p < 0.05 versus IR (obese) group, ∆p < 0.05 versus TIIA (5 mg/kg.d) group, F070p < 0.05 versus TIIA (10 mg/kg.d) group. (n=3).