Review Volume 14, Issue 19 pp 8110—8136

Figure 2. Epigenetically regulated RNA modification in aging-related cardiovascular diseases. (A–C) The biological functions of m6A, m5C and m1A are mediated by writer, eraser, and reader proteins; (D) The role of m7G in mRNA biogenesis in processing and repression of migration; (E, F) The biological functions of PU and uridylation are mediated by writer proteins; (G) A-to-I RNA editing of ADAR modified the mRNA; (H) Potential role of Ac4C in improving mRNA stability.