Research Paper Volume 14, Issue 19 pp 7890—7905
Comprehensive bioinformatics analysis of ribonucleoside diphosphate reductase subunit M2(RRM2) gene correlates with prognosis and tumor immunotherapy in pan-cancer
Figure 4. The miRNAs and transcription factors of RRM2. (A) The correlation of RRM2 expression with miRNA in different tumors. (B) The ceRNA diagram of lncRNA-miRNA-circRNA. The blue dots represent miRNA, green dots lncRNA, and yellow dots circRNA. (C) The transcription factor of RRM2 (p-value < 0.05 and correlation > 0.2). (D) Correlation between RRM2 expression and mismatch repair genes. (E) RRM2 gene expression associated with RNA stemness score (RNAss) and DNA stemness score (DNAss) in different cancers. Red dots indicate a positive correlation and blue dots a negative correlation. *P < 0.05, **P < 0.01, ***P < 0.001.