Research Paper Volume 14, Issue 19 pp 7718—7733
Centenarians consistently present a younger epigenetic age than their chronological age with four epigenetic clocks based on a small number of CpG sites
Figure 1. Description of the four DNA methylation-based epigenetic clocks used in our study. The genomic location of the first and last CpGs analyzed by pyrosequencing are given for each gene. MQR: multiple quadratic regression model, GBR: machine-learning gradient boosting regressor model, MLR: multiple linear regression model.