Research Paper Volume 14, Issue 19 pp 7972—7985
DAZAP1 facilitates the alternative splicing of KITLG to promote multiple myeloma cell proliferation via ERK signaling pathway
Figure 4. DAZAP1 promotes the phosphorylation of ERK in MM cells. (A) A bubble diagram of the top 10 KEGG pathways. In the bubble diagram, the vertical axis indicates the KEGG pathways and the horizontal axis represents the enrichment ratio. The sizes of the dots indicate the number of genes in the Gene Ontology term. (B) Active RAS Pull-down assay and Western blot showed the levels of active form RAS protein compared to total RAS protein. (C and D) WB test examined the phosphorylation level of ERK expression in DAZAP1-OE and siDAZAP1 MM cells.