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Research Paper Volume 14, Issue 20 pp 8270—8291

Combining stem cell rejuvenation and senescence targeting to synergistically extend lifespan

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Figure 2. Expression of OKSM, Sen and OKSM-Sen led to decreased SA-β-gal expression. Levels of b-galactosidase were assessed at day 40 in the following ubiquitous expression experiments using armGal4; tubGal80ts to drive the expression of UAS-OKSM (A), UAS-Sen (B), combination of UAS-Sen and UAS-OKSM (C), and the control UAS-TdTomato at both day 14 (D) and day 40 (E). (F) Results were quantified from five experiments.