Research Paper Volume 14, Issue 20 pp 8437—8447

Gabrb2 knock-out mice exhibit double-directed PMDD-like symptoms: GABAAR subunits, neurotransmitter metabolism disruption, and allopregnanolone binding

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Figure 2. GABAAR receptor subunits changes. (A) The levels of protein expression for 16 different GABA A receptor subunits of WT and KO mouse in the cerebrum (WT male =8, KO male= 8). (B) The levels of protein expression for 16 different GABA A receptor subunits of WT and KO mouse in the cerebellum (WT male =8, KO male=8). Statistical analysis was performed using one-way ANOVA with Newman–Keuls post-hoc test. Average y values ± SEM in the different plots are represented by horizontal bars. *p < 0.05, **p < 0.01, ***p < 0.001.