Research Paper Volume 14, Issue 20 pp 8437—8447
Gabrb2 knock-out mice exhibit double-directed PMDD-like symptoms: GABAAR subunits, neurotransmitter metabolism disruption, and allopregnanolone binding
Figure 3. Neurotransmitters changes. (A) The level of key neurotransmitters in vivo of WT and KO mouse (WT male =8, KO male= 8). (B) The levels of WT and KO mouse in the cerebrum (WT male =8, KO male= 8). (C) The levels of neurotransmitters of WT and KO mouse in the cerebellum (WT male =8, KO male= 8). The levels of GABA, Glu Statistical analysis was performed using one-way ANOVA with Newman–Keuls post-hoc test. Average y values ± SEM in the different plots are represented by horizontal bars. *p < 0.05, **p < 0.01, ***p < 0.001.