Research Paper Volume 14, Issue 20 pp 8568—8580
Identification and validation of genetic signature associated with aging in chronic obstructive pulmonary disease
Figure 2. Age-associated DEGs in COPD model mice. (A) Volcano plot of the 783 age-associated DEGs. Red circle: upregulated genes; blue circles: downregulated genes. (B) Top 10 GO biological processes of the 783 age-associated DEGs. Outer gray circle: a scatter plot for each term of the logFC of the assigned genes; red circles: upregulated genes; blue circles: downregulated genes. (C) All GO cellular components of the 783 age-associated DEGs. (D) Top 13 GO molecular functions of the 783 age-associated DEGs. (E) Top 13 significantly (P<0.05) enriched KEGG pathways. DEGs, differently expressed genes; COPD, chronic obstructive pulmonary disease; GO, gene ontology; FC, fold change; KEGG, Kyoto Encyclopedia of Genes and Genomes.