Research Paper Volume 14, Issue 21 pp 8745—8762

Inhibition of NLRP3 and Golph3 ameliorates diabetes-induced neuroinflammation in vitro and in vivo

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Figure 6. H&E stain of brain tissues of mice treated with NLRP3 inhibitor and Golph3 inhibitor. (A) H&E stain of cortex and hippocampus of mice in DMSO, STZ + DMSO, STZ + ZAF, STZ + BRO, STZ + ZAF + BRO treated groups. (B) Histological score of cortex and hippocampus of mice in of mice in DMSO, STZ + DMSO, STZ + ZAF, STZ + BRO, STZ + ZAF + BRO groups. All data are presented as means ± SEM (n = 8/group). Bar=50μm. * p < 0.05 and ** p < 0.01 compared with control group.