Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 14, Issue 21

15 November, 2022
pp 8582—8881

About the Cover

The cover features Figure 7 " IGF1 gene therapy effect on the activation state of microglia" from Dolcetti et al.

Explore This Issue

Editorial

Enhanced lysosome biogenesis ameliorates neurodegenerative diseases

Wenlong Xue, Yang Li,

https://doi.org/10.18632/aging.204389 pp 8582—8584

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Research Papers

COVID-19
Abnormal myocardial enzymes in the prediction of mortality and hypertension in COVID-19 patients: a retrospective study

Shuang Sha, Min Liu, Miaomiao Sun, Long Xiao, Qing Chang, Ying Chen, Jie Huang,

https://doi.org/10.18632/aging.204362 pp 8585—8594

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ESR1 dysfunction triggers neuroinflammation as a critical upstream causative factor of the Alzheimer’s disease process

Junying Liu, Shouli Yuan, Xinhui Niu, Robbie Kelleher, Helen Sheridan,

https://doi.org/10.18632/aging.204359 pp 8595—8614

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IGF1 gene therapy in middle-aged female rats delays reproductive senescence through its effects on hypothalamic GnRH and kisspeptin neurons

Franco Juan Cruz Dolcetti, Eugenia Falomir-Lockhart, Francisco Acuña, Macarena Lorena Herrera, Sofia Cervellini, Claudio Gustavo Barbeito, Daniela Grassi, Maria-Angeles Arevalo, María José Bellini,

https://doi.org/10.18632/aging.204360 pp 8615—8632

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Epigallocatechin-3-gallate protects porcine oocytes against post-ovulatory aging through inhibition of oxidative stress

Dongjie Zhou, Ming-Hong Sun, Wen-Jie Jiang, Xiao-Han Li, Song-Hee Lee, Geun Heo, Ying-Jie Niu, Sun A. Ock, Xiang-Shun Cui,

https://doi.org/10.18632/aging.204368 pp 8633—8644

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The deubiquitylase USP7 is a novel cyclin F-interacting protein and regulates cyclin F protein stability

Savitha S. Sharma, W. Jack Pledger, Paturu Kondaiah,

https://doi.org/10.18632/aging.204372 pp 8645—8660

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Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging

Tanima SenGupta, Yohan Lefol, Lisa Lirussi, Veronica Suaste, Torben Luders, Swapnil Gupta, Yahyah Aman, Kulbhushan Sharma, Evandro Fei Fang, Hilde Nilsen,

https://doi.org/10.18632/aging.204375 pp 8661—8687

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Efficacy of zinc carnosine in the treatment of colorectal cancer and its potential in combination with immunotherapy in vivo

Weiwei Tang, Hanyuan Liu, Xiao Li, Theng Choon Ooi, Nor Fadilah Rajab, Hongyong Cao, Razinah Sharif,

https://doi.org/10.18632/aging.204380 pp 8688—8699

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Identification and validation of a glycolysis-related gene signature for depicting clinical characteristics and its relationship with tumor immunity in patients with colon cancer

Gang Liu, Xiaoyang Wu, Jian Chen,

https://doi.org/10.18632/aging.204226 pp 8700—8718

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Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants

Yanyan Ling, Chuan Jiang, Zhenzhen Xiao, Xiao Shang, Qi Li, Baojie Wang, Maolin Hao, Fei Liu, Nannan Zhao, Jianli Feng, Hongqin Zhao,

https://doi.org/10.18632/aging.204338 pp 8719—8728

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Deep remission from induction chemotherapy predicts favorable long-term survivals in early stage extranodal nasal NK/T-cell lymphoma receiving sequential chemotherapy and radiation

Fei Qi, Wenyuan Zhou, Yan Xie, Yan Sun, Meng Wu, Yue Chai, Bo Chen, Ningjing Lin, Weiping Liu, Ning Ding, Yexiong Li, Mei Dong, Yuqin Song, Jun Zhu,

https://doi.org/10.18632/aging.204355 pp 8729—8744

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Inhibition of NLRP3 and Golph3 ameliorates diabetes-induced neuroinflammation in vitro and in vivo

Yuan Li, Haifeng Zhang, Weihong Long, Menghan Gao, Weiying Guo, Lu Yu,

https://doi.org/10.18632/aging.204363 pp 8745—8762

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HBP1 inhibits the development of type 2 diabetes mellitus through transcriptional activation of the IGFBP1 gene

Yuning Cheng, Ruixiang Yang, Yue Zhou, Jiyin Wang, Tongjia Zhang, Shujie Wang, Hui Li, Wei Jiang, Xiaowei Zhang,

https://doi.org/10.18632/aging.204364 pp 8763—8782

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Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma

Shaoyan Zheng, Botao Pan,

https://doi.org/10.18632/aging.204369 pp 8783—8804

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Desmocollin-2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma via the ERK/c-MYC signaling pathway

Bo He, Li Guo, Youwen Hu, Hongyan Huang, Lijun Wan, Kedong Xu, Fenfen Wang, Zhili Wen,

https://doi.org/10.18632/aging.204370 pp 8805—8817

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Prognostic and clinicopathological value of m6A regulators in human cancers: a meta-analysis

Zhangci Su, Leyao Xu, Xinning Dai, Mengyao Zhu, Xiaodan Chen, Yuanyuan Li, Jie Li, Ruihan Ge, Bin Cheng, Yun Wang,

https://doi.org/10.18632/aging.204371 pp 8818—8838

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lncRNA HHIP-AS1/HHIP modulates osteogenic differentiation of BM-MSCs by regulating Hedgehog signaling pathway

Xin-Hua Yin, Xiao-Yuan Wang, Shi-Chang Liu, Liang Yan, Bao-Rong He, Ding-Jun Hao, Ming Yang, Zhong-Kai Liu,

https://doi.org/10.18632/aging.204381 pp 8839—8855

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Polydatin administration attenuates the severe sublesional bone loss in mice with chronic spinal cord injury

Jiheng Zhan, Dan Luo, Bingde Zhao, Shudong Chen, Jiyao Luan, Junhua Luo, Yu Hou, Yonghui Hou, Wenke Xu, Wanying Yan, Ji Qi, Xing Li, Qing Zhang, Dingkun Lin,

https://doi.org/10.18632/aging.204382 pp 8856—8875

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Corrections

Correction for: CXCR4 knockdown enhances sensitivity of paclitaxel via the PI3K/Akt/mTOR pathway in ovarian carcinoma

Dan Zi, Qing Li, Cheng-xiong Xu, Zhi-Wei Zhou, Guan-Bin Song, Cheng-Bin Hu, Fang Wen, Han-Lin Yang, Lei Nie, Xing Zhao, Jun Tan, Shu-Feng Zhou, Zhi-Xu He,

https://doi.org/10.18632/aging.204367 pp 8876—8878

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Correction for: Nicotine exposure impairs germ cell development in human fetal ovaries cultured in vitro

Shun-Feng Cheng, Xun-Si Qin, Ze-Li Han, Xiao-Feng Sun, Yan-Ni Feng, Fan Yang, Wei Ge, Lan Li, Yong Zhao, Massimo De Felici, Shu-Hua Zou, Yi Zhou, Wei Shen,

https://doi.org/10.18632/aging.204392 pp 8879—8881

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