Research Paper Volume 14, Issue 21 pp 8661—8687

Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging

class="figure-viewer-img"

Figure 3. Krill oil improves mitochondrial health. (A, B) Representative image and quantification of 8-Oxo (dG) staining in old day 6 PD animals (n = 10 individuals, Error bars, s.e.m; ****p < 0.0001; one-way ANOVA followed by Bonferroni’s multiple comparison test). (C) Oxygen consumption rate in day 1, day 3 and day 6 PD animals (n = 50 individuals, two independent experiments, Error bars, s.e.m; NS and *p < 0.05, **p < 0.01; one-way ANOVA followed by Bonferroni’s multiple comparison test). (D, E) Image and quantification of mitochondrial membrane potential measured using TMRE staining in BJ fibroblast at passage 16 (p16) in the absence and presence of krill oil (n = 6 independent experiments, Scale bar, 20 μm, Error bars, s.e.m; **p < 0.01; one-way ANOVA followed by Bonferroni’s multiple comparison test).